HuagongsheHuagongshe Chemistry Print Report · For research reference only
Divinyl sulfone → [4-(1,1-Dioxo-1lambda6-thiomorpholin-4-yl)-phenyl]-carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Divinyl sulfone | HCID 6496 | — |
| Reactant | tert-Butyl (4-aminophenyl)carbamate | HCID 688611 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | [4-(1,1-Dioxo-1lambda6-thiomorpholin-4-yl)-phenyl]-carbamic acid tert-butyl ester | HCID 68616091 | — |
Reaction Steps
A solution of 408 mg (4-Amino-phenyl)-carbamic acid tert-butyl ester and 254 mg Ethenesulfonyl-ethene in 4 mL EtOH were heated for 30 min at 140° C. under microwave irradiation (100 W, CEM Discover™ apparatus). Then, after cooling to RT the solvents were removed under reduced pressure and the residue was dried in vacuo. The crude product was subjected to the next reaction step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07741341B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-770f859b938246188dc93593dd1d1dc5 |
| Source note | uspto-grants-2010_06 |