HRID1853730

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID31398

N-Chlorosuccinimide

C4H4ClNO2

结构：COc1ccc2[nH]c(=O)c3sccc3c2c1-c1ccc([C@@H](C)NC(=O)OC(C)(C)C)cc1

HCID86689472

未命名化合物

PRODUCTS

生成物

结构：COc1cc(Cl)c2[nH]c(=O)c3sccc3c2c1-c1ccc([C@@H](C)NC(=O)OC(C)(C)C)cc1

HCID86689477

未命名化合物

收率 11%

PROCEDURE

实验过程

Following General Procedure H, (R)-tert-butyl 1-(4-(8-methoxy-4-oxo-4,5-dihydrothieno[2,3-c]quinolin-9-yl)phenyl)ethylcarbamate (300 mg, 0.67 mmol) was reacted with NCS (110 mg, 0.87 mmol) to afford the desired product (27 mg, 11%) as a yellow solid: ESI MS m/z 485 [C25H25ClN2O4S+H]+.