α,α-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzeneacetonitrile → HCID 67450365, compound

Participants

Role	Name	HCID	Charge
Reactant	α,α-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzeneacetonitrile	HCID 59322050	—
Reactant	9-bromo-8-methoxythieno[2,3-c]quinolin-4(5H)-one	HCID 67449139	—
Product	HCID 67450365	HCID 67450365	57.9%

Reaction Steps

Following General Procedure B, 9-bromo-8-methoxythieno[2,3-c]quinolin-4(5H)-one (380 mg, 1.2 mmol) was reacted with 2-methyl-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propanenitrile (500 mg, 1.9 mmol) to afford the desired product (260 mg, 56%) as a brown solid: ESI MS m/z 375 [C22H18N2O2S+H]+.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08962648B2
Source dataset	uspto-grants-2015_02
ORD ID	ord-67dd895114194392a51f066e9bd8556a
Source note	uspto-grants-2015_02