HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(4-bromo-2-methylphenyl)methanesulfonamide → HCID 86689543, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(4-bromo-2-methylphenyl)methanesulfonamide | HCID 669156 | — |
| Reactant | Bis(pinacolato)diborane | HCID 2733548 | — |
| Reactant | 9-bromo-8-methoxythieno[2,3-c]quinolin-4(5H)-one | HCID 67449139 | — |
| Product | HCID 86689543 | HCID 86689543 | 27.3% |
Reaction Steps
Following General Procedure E, N-(4-bromo-2-methylphenyl)methanesulfonamide (130 mg, 0.50 mmol) was reacted with bis(pinacolato)diboron (140 mg, 0.55 mmol) to afford the crude boronic ester which was reacted with 9-bromo-8-methoxythieno[2,3-c]quinolin-4(5H)-one (140 mg, 0.45 mmol) to afford the desired product (51 mg, 27%) as a brown solid: ESI MS m/z 415 [C20H18N2O4S2+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08962648B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-8b9bb8d07536402c81f99a28dfb6b05c |
| Source note | uspto-grants-2015_02 |