HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl 2-(4-bromophenyl)propan-2-ylcarbamate → Tert-butyl 2-(4-(8-methoxy-6-methyl-4-oxo-4,5-dihydrothieno[2,3-c]quinolin-9-yl)phenyl)propan-2-ylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl 2-(4-bromophenyl)propan-2-ylcarbamate | HCID 18183247 | — |
| Reactant | 9-bromo-8-methoxy-6-methylthieno[2,3-c]quinolin-4(5H)-one | HCID 67450006 | — |
| Product | Tert-butyl 2-(4-(8-methoxy-6-methyl-4-oxo-4,5-dihydrothieno[2,3-c]quinolin-9-yl)phenyl)propan-2-ylcarbamate | HCID 86689501 | 79.1% |
Reaction Steps
Following General Procedure E, tert-butyl 2-(4-bromophenyl)propan-2-ylcarbamate (0.44 g, 1.4 mmol) was reacted with 9-bromo-8-methoxy-6-methylthieno[2,3-c]quinolin-4(5H)-one (0.45 g, 1.4 mmol) to afford the desired product (0.53 g, 79%) as a brown solid: ESI MS m/z 479 [C27H30N2O4S+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08962648B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-b5a6c06106a34ab9a0a19b36f0adfda9 |
| Source note | uspto-grants-2015_02 |