tert-butyl N-[(4-bromophenyl)methyl]carbamate → HCID 67447234, compound

HRID 1853810Notes

Reaction equation

HRID 1853810 reaction equation
Br[C:2]1[CH:16]=[CH:15][C:5]([CH2:6][NH:7][C:8](=[O:14])[O:9][C:10]([CH3:13])([CH3:12])[CH3:11])=[CH:4][CH:3]=1.Br[C:18]1[C:19]2[C:20]3[CH:33]=[CH:32][S:31][C:21]=3[C:22](=[O:30])[NH:23][C:24]=2[CH:25]=[CH:26][C:27]=1[O:28][CH3:29]>>[CH3:29][O:28][C:27]1[CH:26]=[CH:25][C:24]2[NH:23][C:22](=[O:30])[C:21]3[S:31][CH:32]=[CH:33][C:20]=3[C:19]=2[C:18]=1[C:2]1[CH:16]=[CH:15][C:5]([CH2:6][NH:7][C:8](=[O:14])[O:9][C:10]([CH3:13])([CH3:12])[CH3:11])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 12453839tert-butyl N-[(4-bromophenyl)methyl]carbamateHCID 674491399-bromo-8-methoxythieno[2,3-c]quinolin-4(5H)-one

Product 1

HCID 67447234HCID 67447234, compoundYield 62%

Procedure

Following General Procedure E, tert-butyl 4-bromobenzylcarbamate (0.78 g, 2.7 mmol) was reacted with 9-bromo-8-methoxythieno[2,3-c]quinolin-4(5H)-one (0.76 g, 2.5 mmol) to afford the desired product (0.66 g, 62%) as a brown solid: ESI MS m/z 437 [C24H24N2O4S+H]+.

Sources & evidence

ORD record
ord-6789703f8b674716b1bfe8930c5677f2
Source dataset
uspto-grants-2015_02
Patent number
US08962648B2

Reaction notes

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