tert-Butyl acetate → 3-Oxo-3-[3-[5-propyl-4-(tetrahydro-pyran-2-yloxymethyl)-thiazol-2-yl]-phenyl]-propionic acid tert-butyl ester
Reaction equation
[C:27]([CH3:28])(=[O:29])[O:30][C:31]([CH3:32])([CH3:33])[CH3:34].[CH3:1][O:2][C:3]([c:4]1[cH:5][c:6](-[c:10]2[s:11][c:12]([CH2:23][CH2:24][CH3:25])[c:13]([CH2:15][O:16][CH:17]3[O:18][CH2:19][CH2:20][CH2:21][CH2:22]3)[n:14]2)[cH:7][cH:8][cH:9]1)=[O:26].[Li:35]>>[C:3]([c:4]1[cH:5][c:6](-[c:10]2[s:11][c:12]([CH2:23][CH2:24][CH3:25])[c:13]([CH2:15][O:16][CH:17]3[O:18][CH2:19][CH2:20][CH2:21][CH2:22]3)[n:14]2)[cH:7][cH:8][cH:9]1)(=[O:26])[CH2:28][C:27](=[O:29])[O:30][C:31]([CH3:32])([CH3:33])[CH3:34]Participants
4
Sources & evidence
- ORD record
- ord-3395de3d275642d69c0ca999dfc6edfa
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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