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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1853897Generated: October 30, 2026

Methyl iodide → HCID 86689560, compound

https://huagongshe.com/reaction/1853897

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantHCID 67450104HCID 67450104—
ProductHCID 86689560HCID 8668956061.5%

Reaction Steps

Following the procedure outlined for Example 628, (R)-4-benzyl-3-(2-(4-bromo-2-fluorophenyl)acetyl)oxazolidin-2-one (4.6 g, 12 mmol) was reacted with methyl iodide (1M solution in toluene, 12.3 mL, 12.3 mmol) to obtain the desired product (3.0 g, 60%) as light yellow solid: ESI MS m/z 407 [C19H17BrFNO3+H]+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08962648B2
Source datasetuspto-grants-2015_02
ORD IDord-4560be61dd0f4729baea1f8eab400a48
Source noteuspto-grants-2015_02