HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → HCID 86689560, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | HCID 67450104 | HCID 67450104 | — |
| Product | HCID 86689560 | HCID 86689560 | 61.5% |
Reaction Steps
Following the procedure outlined for Example 628, (R)-4-benzyl-3-(2-(4-bromo-2-fluorophenyl)acetyl)oxazolidin-2-one (4.6 g, 12 mmol) was reacted with methyl iodide (1M solution in toluene, 12.3 mL, 12.3 mmol) to obtain the desired product (3.0 g, 60%) as light yellow solid: ESI MS m/z 407 [C19H17BrFNO3+H]+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08962648B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-4560be61dd0f4729baea1f8eab400a48 |
| Source note | uspto-grants-2015_02 |