Ethyl Bromide → 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)butanenitrile

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Ethyl Bromide	HCID 6332	—
Edukt	2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetonitrile	HCID 3842922	—
Produkt	2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)butanenitrile	HCID 67449517	59,7%

Reaktionsschritte

Following the procedure outlined for Example 649, 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetonitrile (5.2 g, 21 mmol)) was reacted with ethyl bromide (2.6 g, 24 mmol) to afford the desired product (3.4 g, 59%) as colorless oil: ESI MS m/z 272 [C16H22BNO2+H]+.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08962648B2
Quelldatensatz	uspto-grants-2015_02
ORD ID	ord-22cd0c537d584dc4b18792b0886f9ec6
Quellennotiz	uspto-grants-2015_02