HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → Benzenemethanamine, 4-bromo-N-methyl-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 4-Bromobenzyl bromide | HCID 68527 | — |
| Product | Benzenemethanamine, 4-bromo-N-methyl- | HCID 485400 | 93.7% |
Reaction Steps
Following the procedure outlined for Example 488, 1-bromo-4-(bromomethyl)benzene (1.0 g, 4.0 mmol) was reacted with methanamine (620 mg, 20 mmol) to afford the desired product (750 mg, 93%) as a brown solid: ESI MS m/z 201 [C8H10BrN+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08962648B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-4187f1507229459698bdb552b70723bc |
| Source note | uspto-grants-2015_02 |