HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Boc-amino)piperidine → HCID 86689495, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Boc-amino)piperidine | HCID 4233041 | — |
| Reactant | 3-Chloropropenyl-1-boronic acid pinacol ester | HCID 11830500 | — |
| Product | HCID 86689495 | HCID 86689495 | 34.9% |
Reaction Steps
Following the procedure outlined for Example 488, (E)-2-(3-chloroprop-1-enyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (500 mg, 2.5 mmol) was reacted with tert-butyl piperidin-3-ylcarbamate (740 mg, 3.7 mmol) to afford the desired product (320 mg, 24%) as a yellow oil: ESI MS m/z 367 [C19H35BN2O4+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08962648B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-a7ff1d5cf31b4202892fcd75603e269c |
| Source note | uspto-grants-2015_02 |