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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1854179Generated: November 4, 2026

Tert-Butylamine → 5-(tert-Butyl)-3-((tert-butylamino)methyl)-2',4'-dichloro-[1,1'-biphenyl]-2-ol hydrochloride

https://huagongshe.com/reaction/1854179

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-ButylamineHCID 6385—
Reactant5-(tert-Butyl)-2',4'-dichloro-2-hydroxy-[1,1'-biphenyl]-3-carbaldehydeHCID 86718724—
Product5-(tert-Butyl)-3-((tert-butylamino)methyl)-2',4'-dichloro-[1,1'-biphenyl]-2-ol hydrochlorideHCID 86718725—

Reaction Steps

5-(tert-Butyl)-3-((tert-butylamino)methyl)-2′,4′-dichloro-[1,1′-biphenyl]-2-ol hydrochloride was prepared as a gray solid using the procedure described in Example 9 from 5-(tert-butyl)-2′,4′-dichloro-2-hydroxy-[1,1′-biphenyl]-3-carbaldehyde and tert-butylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08962657B2
Source datasetuspto-grants-2015_02
ORD IDord-5adffd1f1bf14933803e705315afd6d7
Source noteuspto-grants-2015_02