Ethyl 5-amino-1-(2-fluorophenyl)-1H-pyrazole-3-carboxylate → HCID 70664734, compound

HRID 1854527Notes

Reaction equation

HRID 1854527 reaction equation
F[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[C:12]([N:13]2[CH2:17][CH2:16][CH2:15][CH2:14]2)=[CH:11][C:10]([C:18]([OH:20])=[O:19])=[N:9]1.C(OC(C1C=C(N)N(C2C=CC=CC=2F)N=1)=O)C>>[C:3]1([N:8]2[C:12]([N:13]3[CH2:14][CH2:15][CH2:16][CH2:17]3)=[CH:11][C:10]([C:18]([OH:20])=[O:19])=[N:9]2)[CH:2]=[CH:7][CH:6]=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 53302142Ethyl 5-amino-1-(2-fluorophenyl)-1H-pyrazole-3-carboxylateHCID 70665263HCID 70665263, compound

Product 1

HCID 70664734HCID 70664734, compound

Procedure

According to this procedure 1-(2-Fluoro-phenyl)-5-pyrrolidin-1-yl-1H-pyrazole-3-carboxylic acid is prepared starting from 5-Amino-1-(2-fluoro-phenyl)-1H-pyrazole-3-carboxylic acid ethyl ester

Workup

  1. customis prepared

Sources & evidence

ORD record
ord-3f20780a69ff4743808b7a003f186e65
Source dataset
uspto-grants-2015_02
Patent number
US08962671B2

Reaction notes

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