Ethyl 5-amino-1-(2-fluorophenyl)-1H-pyrazole-3-carboxylate → HCID 68202333, compound

HRID 1854528Notes

Reaction equation

HRID 1854528 reaction equation
[O:1]=[S:2]1(=[O:21])[CH2:6][CH2:5][CH2:4][N:3]1[C:7]1[N:11]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[N:10]=[C:9]([C:18]([OH:20])=[O:19])[CH:8]=1.C(OC(C1C=C(N)N(C2C=CC=CC=2[F:39])N=1)=O)C>>[O:21]=[S:2]1(=[O:1])[CH2:6][CH2:5][CH2:4][N:3]1[C:7]1[N:11]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=2[F:39])[N:10]=[C:9]([C:18]([OH:20])=[O:19])[CH:8]=1

Participants

3

Reactant 2

HCID 53302142Ethyl 5-amino-1-(2-fluorophenyl)-1H-pyrazole-3-carboxylateHCID 125482156HCID 125482156, compound

Product 1

HCID 68202333HCID 68202333, compound

Procedure

According to this procedure 5-(1,1-Dioxo-1lambda*6*-isothiazolidin-2-yl)-1-phenyl-1H-pyrazole-3-carboxylic acid is prepared starting from 5-Amino-1-(2-fluoro-phenyl)-1H-pyrazole-3-carboxylic acid ethyl ester.

Workup

  1. customis prepared

Sources & evidence

ORD record
ord-8b590ec9951d469fbe1c69b57b5078e2
Source dataset
uspto-grants-2015_02
Patent number
US08962671B2

Reaction notes

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