(3S)-3-Amino-3-(2-methylphenyl)propanoic acid → HCID 60143202, compound

HRID 1854539Notes

Reaction equation

HRID 1854539 reaction equation
[CH3:1][C:2]([CH3:22])([CH3:21])[C:3](=[O:20])[CH2:4][NH:5][C:6]1[N:10]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[N:9]=[C:8]([C:17]([OH:19])=O)[CH:7]=1.[NH2:23][C@H:24]([C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=1[CH3:35])[CH2:25][C:26]([OH:28])=[O:27]>>[CH3:21][C:2]([CH3:1])([CH3:22])[C:3](=[O:20])[CH2:4][NH:5][C:6]1[N:10]([C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=2)[N:9]=[C:8]([C:17]([NH:23][C@H:24]([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=2[CH3:35])[CH2:25][C:26]([OH:28])=[O:27])=[O:19])[CH:7]=1

Participants

3

Reactant 2

HCID 6934180(3S)-3-Amino-3-(2-methylphenyl)propanoic acidHCID 70665037HCID 70665037, compound

Product 1

HCID 60143202HCID 60143202, compound

Procedure

This synthesis is carried out by combination of 5-(3,3-Dimethyl-2-oxo-butylamino)-1-phenyl-1H-pyrazole-3-carboxylic acid and (S)-3-Amino-3-o-tolyl-propionic acid applying General Procedure A.

Sources & evidence

ORD record
ord-c002be7f985745408ad0fbc14731e4e5
Source dataset
uspto-grants-2015_02
Patent number
US08962671B2

Reaction notes

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