HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-4,6-dimethoxy-1,3,5-triazine → 3-(4,6-dimethoxy-1,3,5-triazin-2-yl)-5-methoxy-1,3-dihydro-2H-indol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-4,6-dimethoxy-1,3,5-triazine | HCID 18450 | — |
| Reactant | 5-Methoxyoxindole | HCID 1514286 | — |
| Product | 3-(4,6-dimethoxy-1,3,5-triazin-2-yl)-5-methoxy-1,3-dihydro-2H-indol-2-one | HCID 86706733 | — |
Reaction Steps
5-Methoxy-1,3-dihydro-2H-indol-2-one (1.59 g) and 2-chloro-4,6-dimethoxy-1,3,5-triazine (1.97 g) are reacted analogously to Example 1 Variant A. This gives the title compound as solid in an HPLC purity of 92% area (1.39 g, 53% of theory).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08962828B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-148b29e8b301446c9d1d03a876dfff98 |
| Source note | uspto-grants-2015_02 |