3-(Methylsulfanyl)-1,2,4-triazine → HCID 77230911, compound

HRID 1854809Notes

Reaction equation

HRID 1854809 reaction equation
[NH:1]1[CH2:6][CH2:5][CH:4]([NH2:7])[CH2:3][CH2:2]1.CS[C:10]1[N:11]=[N:12][CH:13]=[CH:14][N:15]=1.N1(C2N=NC=CN=2)CCNCC1>>[N:12]1[CH:13]=[CH:14][N:15]=[C:10]([N:1]2[CH2:6][CH2:5][CH:4]([NH2:7])[CH2:3][CH2:2]2)[N:11]=1

Participants

4

Reactant 3

HCID 3218393-(Methylsulfanyl)-1,2,4-triazineHCID 4243614-PiperidinamineHCID 12296696HCID 12296696, compound

Product 1

HCID 77230911HCID 77230911, compound

Procedure

Intermediate 5b is synthesised from piperidin-4-ylamine and the precursor 2a according to the procedure described for the synthesis of 5a. Intermediate 5b is isolated in solid form with a 71% yield.

Sources & evidence

ORD record
ord-e179c1b2258d4ddabcfb6fb3f0e39450
Source dataset
uspto-grants-2015_02
Patent number
US08962837B2

Reaction notes

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