HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → N,N-dibutyl-N-(3-phenoxypropyl)amine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | N-butyl-N-(3-phenoxypropyl)butan-1-amine | HCID 5262101 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | N,N-dibutyl-N-(3-phenoxypropyl)amine hydrochloride | HCID 22629982 | 107.2% |
Reaction Steps
297.3 g (1.13 mol) of the N,N-dibutyl-N-(3-phenoxypropyl)amine isolated previously are stirred in 600 ml of DCE, and 148.9 g (1.469 mol; 1.3 eq.) of 36% HCl are added, at 20° C. The mixture is stirred for 1 hour at this temperature and dried by azeotropic distillation with DCE until a water content ≦0.01% is obtained, and is then concentrated under vacuum. 363.1 g of N,N-dibutyl-N-(3-phenoxypropyl)amine hydrochloride are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08962869B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-2eedfd5f536f4c7b93d470ed613a246e |
| Source note | uspto-grants-2015_02 |