3-methoxy-4-(4-methyl-1H-imidazol-1-yl)aniline → HCID 44192502, compound

HRID 1855329Notes

Reaction equation

HRID 1855329 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([NH2:15])[CH:6]=[CH:7][C:8]=1[N:9]1[CH:13]=[C:12]([CH3:14])[N:11]=[CH:10]1.Cl[C:17]1[N:22]=[C:21]([CH2:23][C:24]2[CH:29]=[CH:28][CH:27]=[C:26]([Cl:30])[CH:25]=2)[CH:20]=[CH:19][N:18]=1>>[Cl:30][C:26]1[CH:25]=[C:24]([CH:29]=[CH:28][CH:27]=1)[CH2:23][C:21]1[CH:20]=[CH:19][N:18]=[C:17]([NH:15][C:5]2[CH:6]=[CH:7][C:8]([N:9]3[CH:13]=[C:12]([CH3:14])[N:11]=[CH:10]3)=[C:3]([O:2][CH3:1])[CH:4]=2)[N:22]=1

Participants

3

Reactant 2

HCID 454801813-methoxy-4-(4-methyl-1H-imidazol-1-yl)anilineHCID 86633616HCID 86633616, compound

Product 1

HCID 44192502HCID 44192502, compoundYield 55%

Procedure

The title compound was prepared in analogous manner as described in example 1e) from 3-methoxy-4-(4-methyl-imidazol-1-yl)-phenylamine and 2-chloro-4-(3-chloro-benzyl)-pyrimidine. It was obtained as a yellow solid in 55% yield.

Workup

  1. customIt was obtained as a yellow solid in 55% yield

Sources & evidence

ORD record
ord-92c6772690ba4804b0198ad1afd2a35d
Source dataset
uspto-grants-2015_02
Patent number
US08962834B2

Reaction notes

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