3-Cyanophenol → HCID 57829794, compound

HRID 1855341Notes

Reaction equation

HRID 1855341 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=1)[C:5]#[N:6].Cl[C:11]1[CH:16]=[C:15]([CH3:17])[N:14]=[C:13]([NH:18][C:19]2[CH:24]=[CH:23][C:22]([N:25]3[CH:29]=[C:28]([CH3:30])[N:27]=[CH:26]3)=[C:21]([O:31][CH3:32])[CH:20]=2)[N:12]=1>>[CH3:32][O:31][C:21]1[CH:20]=[C:19]([NH:18][C:13]2[N:12]=[C:11]([O:1][C:2]3[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=3)[C:5]#[N:6])[CH:16]=[C:15]([CH3:17])[N:14]=2)[CH:24]=[CH:23][C:22]=1[N:25]1[CH:29]=[C:28]([CH3:30])[N:27]=[CH:26]1

Participants

3

Reactant 2

HCID 133943-CyanophenolHCID 57829826HCID 57829826, compound

Product 1

HCID 57829794HCID 57829794, compoundYield 75%

Procedure

The title compound was prepared in analogous manners as described in example 9) from 3-hydroxy-benzonitrile and (4-chloro-6-methyl-pyrimidin-2-yl)-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-amine. It was obtained in 75% yield as a pale-brown solid. MS ISP (m/e): 413.4 (100) [(M+H)+].

Workup

  1. customIt was obtained in 75% yield as a pale-brown solid

Sources & evidence

ORD record
ord-d248ec4cbe7d40cc861522716f2b2d77
Source dataset
uspto-grants-2015_02
Patent number
US08962834B2

Reaction notes

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