Butane-1,3-dione, 4,4,4-trifluoro-1-(4-imidazol-1-ylphenyl)- → [4-(4-Imidazol-1-yl-phenyl)-6-trifluoromethyl-pyrimidin-2-yl]-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-amine

Participants

Reaction Steps

The title compound was prepared from 4,4,4-trifluoro-1-(4-imidazol-1-yl-phenyl)-butane-1,3-dione (137 mg, 0.49 mmol) and N-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-guanidine dinitrate (180 mg, 0.49 mmol) using in analogous manner the procedure described in example 29). Obtained as a pale-yellow solid (19 mg, 8%). Mp 248-250° C.

Provenance & Evidence