(2E)-1-(4-chlorophenyl)-3-(dimethylamino)prop-2-en-1-one → [4-(4-Chloro-phenyl)-pyrimidin-2-yl-3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-amine

関与物質

反応手順

The title compound was prepared from crude 1-(4-chloro-phenyl)-3-dimethylamino-propenone (87 mg, 0.3 mmol) and N-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-guanidine dinitrate (83 mg, 0.22 mmol) using in analogous manner the procedure described in example 28b). Obtained as a pale-yellow solid (29 mg, 33%). Mp 202-204° C.

情報源と証拠