HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-fluoro-4-(2-methyl-1H-imidazol-1-yl)aniline → (4-Benzyl-6-methyl-pyrimidin-2-yl)-[3-fluoro-4-(2-methyl-imidazol-1-yl)-phenyl]-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-fluoro-4-(2-methyl-1H-imidazol-1-yl)aniline | HCID 21876620 | — |
| Reactant | 4-Benzyl-2-chloro-6-methyl-pyrimidine | HCID 86633618 | — |
| Product | (4-Benzyl-6-methyl-pyrimidin-2-yl)-[3-fluoro-4-(2-methyl-imidazol-1-yl)-phenyl]-amine | HCID 57829796 | — |
Reaction Steps
The title compound was prepared from 3-fluoro-4-(2-methyl-imidazol-1-yl)-phenylamine (87 mg, 0.46 mmol) and 4-benzyl-2-chloro-6-methyl-pyrimidine (100 mg, 0.46 mmol) in analogous manner to the procedure described in example 1e). Obtained as a light yellow oil (140 mg, 82%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08962834B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-ceede4dd4ae14ee4a70b3f5f44c8015a |
| Source note | uspto-grants-2015_02 |