HCID 68911546, compound → HCID 57829841, compound

HRID 1855384Notes

Reaction equation

HRID 1855384 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([NH2:14])[CH:6]=[CH:7][C:8]=1[C:9]1[S:13][CH:12]=[N:11][CH:10]=1.[CH2:15]([C:22]1[CH:27]=[C:26]([CH3:28])[N:25]=[C:24](Cl)[N:23]=1)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[CH2:15]([C:22]1[CH:27]=[C:26]([CH3:28])[N:25]=[C:24]([NH:14][C:5]2[CH:6]=[CH:7][C:8]([C:9]3[S:13][CH:12]=[N:11][CH:10]=3)=[C:3]([O:2][CH3:1])[CH:4]=2)[N:23]=1)[C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1

Participants

3

Reactant 2

HCID 68911546HCID 68911546, compoundHCID 866336184-Benzyl-2-chloro-6-methyl-pyrimidine

Product 1

HCID 57829841HCID 57829841, compound

Procedure

The title compound was prepared from 3-methoxy-4-thiazol-5-yl-phenylamine (118 mg, 0.57 mmol) and 4-benzyl-2-chloro-6-methyl-pyrimidine (125 mg, 0.57 mmol) in analogous manner to the procedure described in example 1e). Obtained as a colorless wax (70 mg, 32%).

Workup

  1. customObtained as a colorless wax (70 mg, 32%)

Sources & evidence

ORD record
ord-37d3f48c1e914486b239520482eee1d5
Source dataset
uspto-grants-2015_02
Patent number
US08962834B2

Reaction notes

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