4-tert-Butylphenol → HCID 62477121, compound

HRID 1855422Notes

Reaction equation

HRID 1855422 reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([OH:11])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[Cl:12][C:13]1[N:18]=[C:17](Cl)[CH:16]=[C:15]([CH3:20])[N:14]=1>>[C:1]([C:5]1[CH:6]=[CH:7][C:8]([O:11][C:17]2[CH:16]=[C:15]([CH3:20])[N:14]=[C:13]([Cl:12])[N:18]=2)=[CH:9][CH:10]=1)([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 73934-tert-ButylphenolHCID 794712,4-Dichloro-6-methylpyrimidine

Product 1

HCID 62477121HCID 62477121, compoundYield 51%

Procedure

Prepared in analogy to example 81a) from 4-t-butylphenol and 2,4-dichloro-6-methylpyrimidine in a yield of 51%. 1H NMR (CDCl3, 300 MHz): δ (ppm)=7.44 (d, 2H), 7.07 (d, 2H), 6.54 (s, 1H), 2.45 (s, 3H), 1.35 (s, 9H).

Sources & evidence

ORD record
ord-5a790e8319e149b2aa786e91a1f63463
Source dataset
uspto-grants-2015_02
Patent number
US08962834B2

Reaction notes

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