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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1855432Generated: October 30, 2026

(2-chloro-6-methyl-pyrimidin-4-yl)-diethyl-amine → HCID 44193276, compound

https://huagongshe.com/reaction/1855432

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-chloro-6-methyl-pyrimidin-4-yl)-diethyl-amineHCID 12315789—
Reactant3-methoxy-4-(4-methyl-1H-imidazol-1-yl)anilineHCID 45480181—
ProductHCID 44193276HCID 4419327665%

Reaction Steps

The title compound was prepared from 3-methoxy-4-(4-methyl-imidazol-1-yl)-phenylamine (67 mg, 0.33 mmol) and (2-chloro-6-methyl-pyrimidin-4-yl)-diethyl-amine (67 mg, 0.33 mmol) in analogous manner as described in example 90. It was obtained in 65% yield as a light yellow viscous oil. MS ISP (m/e): 367.2 (100) [(M+H)+]. 1H NMR (DMSO-D6, 300 MHz): δ (ppm)=9.15 (s, 1H), 7.88 (s, 1H), 7.63 (s, 1H), 7.32 (d, 1H), 7.16 (d, 1H), 7.01 (s, 1H), 6.00 (s, 1H), 3.78 (s, 3H), 3.51 (br q, 4H), 2.20 (s, 3H), 2.14 (s, 3H), 1.13 (t, 6H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08962834B2
Source datasetuspto-grants-2015_02
ORD IDord-6a8b317151d0434cb2e75af5acb4ac77
Source noteuspto-grants-2015_02