HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-chloro-6-methyl-pyrimidin-4-yl)-diethyl-amine → HCID 44193276, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-chloro-6-methyl-pyrimidin-4-yl)-diethyl-amine | HCID 12315789 | — |
| Reactant | 3-methoxy-4-(4-methyl-1H-imidazol-1-yl)aniline | HCID 45480181 | — |
| Product | HCID 44193276 | HCID 44193276 | 65% |
Reaction Steps
The title compound was prepared from 3-methoxy-4-(4-methyl-imidazol-1-yl)-phenylamine (67 mg, 0.33 mmol) and (2-chloro-6-methyl-pyrimidin-4-yl)-diethyl-amine (67 mg, 0.33 mmol) in analogous manner as described in example 90. It was obtained in 65% yield as a light yellow viscous oil. MS ISP (m/e): 367.2 (100) [(M+H)+]. 1H NMR (DMSO-D6, 300 MHz): δ (ppm)=9.15 (s, 1H), 7.88 (s, 1H), 7.63 (s, 1H), 7.32 (d, 1H), 7.16 (d, 1H), 7.01 (s, 1H), 6.00 (s, 1H), 3.78 (s, 3H), 3.51 (br q, 4H), 2.20 (s, 3H), 2.14 (s, 3H), 1.13 (t, 6H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08962834B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-6a8b317151d0434cb2e75af5acb4ac77 |
| Source note | uspto-grants-2015_02 |