5-Bromo-2-fluorobenzonitrile → 5-bromo-2-(4-methyl-1H-imidazol-1-yl)benzonitrile

HRID 1855460Notes

Reaction equation

HRID 1855460 reaction equation
[Br:1][C:2]1[CH:3]=[CH:4][C:5](F)=[C:6]([CH:9]=1)[C:7]#[N:8].[CH3:11][C:12]1[N:13]=[CH:14][NH:15][CH:16]=1>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([N:15]2[CH:16]=[C:12]([CH3:11])[N:13]=[CH:14]2)=[C:6]([CH:9]=1)[C:7]#[N:8]

Participants

3

Reactant 2

HCID 27249005-Bromo-2-fluorobenzonitrileHCID 178418800HCID 178418800, compound

Product 1

HCID 669615175-bromo-2-(4-methyl-1H-imidazol-1-yl)benzonitrile

Procedure

This compound was prepared from 5-bromo-2-fluorobenzonitrile and 4-methylimidazole, as described in US2006/0004013.

Sources & evidence

ORD record
ord-d1b9822b3de54abc898cf817392117ae
Source dataset
uspto-grants-2015_02
Patent number
US08962834B2

Reaction notes

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