HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-Butylamine → n-Tert-butylpropanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-Butylamine | HCID 6385 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Propionyl chloride | HCID 62324 | — |
| Reactant | N-tert-Butylpivalamide | HCID 299326 | — |
| Product | n-Tert-butylpropanamide | HCID 239177 | 95% |
Reaction Steps
In a fashion similar to the preparation of LtBu,tBuH, treatment of tert-butylamine (11.3 mL, 105 mmol) and triethylamine (14.9 mL, 105 mmol) with propionyl chloride (8.9 mL, 100 mmol) afforded LEt,tBuH as white crystalline solid (12.27 g, 95%) upon sublimation at 55° C./0.05 Torr: mp 90-92° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08962876B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-7743c2ad4b9a452c93861ccb22f30fd0 |
| Source note | uspto-grants-2015_02 |