HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexylamine → HCID 23347815, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexylamine | HCID 7965 | — |
| Reactant | Ethyl 1-methyl-alpha-oxo-1H-pyrrole-2-acetate | HCID 89094 | — |
| Catalyst | Titanium Tetrachloride | HCID 24193 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | Pentane | HCID 8003 | — |
| Product | HCID 23347815 | HCID 23347815 | 15% |
Reaction Steps
To a solution of 25 g ethyl 1-methylpyrrole-2-glyoxylate and 44.5 g cyclohexylamine in 700 ml ether under nitrogen at 0° C. is added 8.8 ml of titanium tetrachloride in 80 ml pentane. After stirring at room temperature overnight, the precipitate is removed by filtration. The filtrate is evaporated and the resulting oil distilled. The fraction collected at 111°-117° C. (5 millitorr) is crystallized from hexane to afford a 15% yield of ethyl α-cyclohexylimino-1-methylpyrrole-2-acetate, m.p. 35°-36° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04216150 |
| Source dataset | uspto-grants-1980_08 |
| ORD ID | ord-dc0335ebc12a49229b0f612b77124da1 |
| Source note | uspto-grants-1980_08 |