HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → N-acetyl-3-chloropropionamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 3-Chloropropanamide | HCID 79982 | — |
| Product | N-acetyl-3-chloropropionamide | HCID 12837854 | — |
Reaction Steps
A mixture of 0.2 mole 3-chloropropionamide, 35 ml. of acetic anhydride and 1 ml. acetylchloride is refluxed under nitrogen for 1 hour and then concentrated in vacuo to give crude N-acetyl-3-chloropropionamide as an oil which is used in the next step without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04216160 |
| Source dataset | uspto-grants-1980_08 |
| ORD ID | ord-5118e11033df4537959d7080f7cd1a76 |
| Source note | uspto-grants-1980_08 |