HRID1855798

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID176

Acetic Acid

C2H4O2

HCID14797

Potassium hydroxide

HKO

结构：CCOC(=O)/C=C(C)/C=C/C=C(C)/C=C/c1c(C)oc(C)c1C

HCID86737131

未命名化合物

PRODUCTS

生成物

$结构：CC(/C=C/c1c(C)oc(C)c1C)=C\C=C\C(C)=C\C(=O)O$

HCID23349112

未命名化合物

收率 58.8%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID702

Ethanol

C2H6O

溶剂HCID962

Water

H2O

2 次

PROCEDURE

实验过程

(E,E,E,E)-3,7-Dimethyl-9-(2,4,5-trimethyl-3-furyl)-2,4,6,8-nonatetraenoic acid ethyl ester (2.8 g.) was dissolved in ethanol (50 ml.) treated with potassium hydroxide (1.6 g.) in water (5 ml.) and heated at reflux for 30 minutes. After cooling to room temperature, water followed by acetic acid (until acid) was added and the solids were filtered off. Crystallization from ethylacetate gave pure (E,E,E,E)-3,7-dimethyl-9-(2,4,5-trimethyl-3-furyl)-2,4,6,8-nonatetraenoic acid (1.5 g.) m.p. 213°-214°.

WORKUP

后处理

temperatureheated
temperatureat reflux for 30 minutes
additionwas added
filtrationthe solids were filtered off
customCrystallization from ethylacetate