HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 14338588, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 14338583 | HCID 14338583 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 14338588 | HCID 14338588 | 89% |
Reaction Steps
5-(2-Thienylmethyl)-2-thiouracil (4.5 g) was warmed at 65° with a mixture of methyl iodide (2.8 g), sodium hydroxide (0.8 g), water (75 ml) and ethanol (150 ml) to give 5-(2-thienylmethyl)-2-methylthio-4-pyrimidone (89%) m.p. 170.5°-171.5° (ethanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04216318 |
| Source dataset | uspto-grants-1980_08 |
| ORD ID | ord-1b83180d796c418d87541a72622690b8 |
| Source note | uspto-grants-1980_08 |