HCID 54075889, compound → Ethyl 3-(2-thiazolyl)propionate

HRID 1855847Notes

Reaction equation

HRID 1855847 reaction equation
[S:1]1[CH:5]=[CH:4][N:3]=[C:2]1[CH:6]=[CH:7][C:8]([O:10][CH2:11][CH3:12])=[O:9]>C(O)C.[Pd]>[S:1]1[CH:5]=[CH:4][N:3]=[C:2]1[CH2:6][CH2:7][C:8]([O:10][CH2:11][CH3:12])=[O:9]

Participants

4

Reactant 1

HCID 54075889HCID 54075889, compound

Product 1

HCID 14338578Ethyl 3-(2-thiazolyl)propionate

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Ethyl 2-thiazoleacrylate (14.8 g) was dissolved in ethanol (170 ml) and hydrogenated at 40° and a pressure of 50 psi using 10% Palladium on charcoal to give ethyl 2-thiazolepropionate.

Sources & evidence

ORD record
ord-27886d705de440eda86e817bbaab1f0e
Source dataset
uspto-grants-1980_08
Patent number
US04216318

Reaction notes

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