3-Pyridylmethyl-2-methylthio-4-pyrimidone → HCID 23349188, compound

HRID 1855858Notes

Reaction equation

HRID 1855858 reaction equation
[ClH:1].Cl.Cl.[CH3:4][C:5]1[NH:9][CH:8]=[N:7][C:6]=1[CH2:10][S:11][CH2:12][CH2:13][CH2:14][NH:15][C:16]1[NH:21][C:20](=[O:22])[C:19]([CH2:23][C:24]2[CH:25]=NC=[CH:28][CH:29]=2)=[CH:18][N:17]=1.[N:30]1C=CC=C(CC2C(=O)NC(SC)=NC=2)[CH:31]=1>>[ClH:1].[ClH:1].[ClH:1].[CH3:4][C:5]1[NH:9][CH:8]=[N:7][C:6]=1[CH2:10][S:11][CH2:12][CH2:13][CH2:14][NH:15][C:16]1[NH:21][C:20](=[O:22])[C:19]([CH2:23][C:24]2[CH:29]=[CH:28][N:30]=[CH:31][CH:25]=2)=[CH:18][N:17]=1

Participants

3

Reactant 2

HCID 127838233-Pyridylmethyl-2-methylthio-4-pyrimidoneHCID 20279289HCID 20279289, compound

Product 1

HCID 23349188HCID 23349188, compound

Procedure

In a similar manner 2-[3-(5-methyl-4-imidazolylmethylthio)propylamino]-5-(3-pyridylmethyl)-4-pyrimidone trihydrochloride m.p. 184°-189° was prepared from 5-(3-pyridylmethyl-2-methylthio-4-pyrimidone.

Sources & evidence

ORD record
ord-c5bbe388ab7a42e0950b88815347fd17
Source dataset
uspto-grants-1980_08
Patent number
US04216318

Reaction notes

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