HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 2-Methylthio-5-[1-(3-pyridyl)ethyl]-4-pyrimidone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Sodium ethoxide | HCID 2723922 | — |
| Reactant | HCID 13505307 | HCID 13505307 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Methylthio-5-[1-(3-pyridyl)ethyl]-4-pyrimidone | HCID 13505309 | — |
Reaction Steps
Treatment of 5-(1-(3-pyridyl)ethyl)-2-thiouracil with methyl iodide and sodium ethoxide in ethanol at 0°, followed by acidification gave 2-methylthio-5-[1-(3-pyridyl)ethyl]-4-pyrimidone m.p. 201°-204°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04216318 |
| Source dataset | uspto-grants-1980_08 |
| ORD ID | ord-fde1d3880e1d4f17893abaabbd032d44 |
| Source note | uspto-grants-1980_08 |