3-Benzylpyridine → 3-Benzylpiperidine

HRID 1855883Notes

Reaction equation

HRID 1855883 reaction equation
[CH2:1]([C:8]1[CH:9]=[N:10][CH:11]=[CH:12][CH:13]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(O)(=O)C.[Pt]=O>[CH2:1]([CH:8]1[CH2:13][CH2:12][CH2:11][NH:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 1

HCID 121123-Benzylpyridine

Product 1

HCID 1145513-Benzylpiperidine

Reagents, catalysts & solvents 2

HCID 82844Platinum oxide (PtO)CatalystHCID 176Acetic AcidSolvent

Procedure

Catalytic reduction of 3-benzylpyridine in glacial acetic acid over a platinum oxide catalyst and isolation of the product using the procedure described above in Preparation 1 affords 3-benzylpiperidine.

Workup

  1. customdescribed above in Preparation 1

Sources & evidence

ORD record
ord-e33a02ea6bd24aad865003c7ba7930ad
Source dataset
uspto-grants-1980_08
Patent number
US04216326

Reaction notes

Loading…