1H-1,2,4-Triazole → HCID 12816738, compound

HRID 1855919Notes

Reaction equation

HRID 1855919 reaction equation
[CH3:1][C:2]([CH3:14])([C:4](=[O:13])[CH:5]=[CH:6][C:7](=[O:12])[C:8]([CH3:11])([CH3:10])[CH3:9])[CH3:3].[NH:15]1[CH:19]=[N:18][CH:17]=[N:16]1>C1(C)C=CC=CC=1>[N:15]1([CH:5]([CH2:6][C:7](=[O:12])[C:8]([CH3:11])([CH3:10])[CH3:9])[C:4](=[O:13])[C:2]([CH3:14])([CH3:1])[CH3:3])[CH:19]=[N:18][CH:17]=[N:16]1

Participants

4

Reactant 2

HCID 92571H-1,2,4-TriazoleHCID 54363564HCID 54363564, compound

Product 1

HCID 12816738HCID 12816738, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

2,2,7,7-tetramethyl-oct-4-en-3,6-dione (0.01 mol) and 1,2,4-triazole (0.01 mol), suspended in toluene (100 ml), were refluxed for 24 hours. On cooling to room temperature, the organic layer was washed with water (4×100 ml) and dried over sodium sulphate. Removal of the solvent gave 4-(1,2,4-triazol-1-yl)-2,2,7,7-tetramethyl-octan-3,6-dione, m.p. 66°-69°.

Workup

  1. temperaturewere refluxed for 24 hours
  2. washthe organic layer was washed with water (4×100 ml)
  3. dry with materialdried over sodium sulphate
  4. customRemoval of the solvent

Sources & evidence

ORD record
ord-14e9d4cb987b4ea2bd38604c1de7acfe
Source dataset
uspto-grants-1980_08
Patent number
US04217129

Reaction notes

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