Methane → HCID 178496764, compound

Participants

Reaction Steps

The mixture of the compound of Example I (31 g, 0.073 mole), ethanol (350 ml) and 5% Pd/C-50% H2O (1.5 g) was subjected to hydrogenation for 5 hours at room temperature, using 14.0 psia H2 (theory: 14.7 psia). Methanol (1000 ml) was added to the reaction mixture. The mixture was heated, treated with Darco, filtered, and the filtrate was reduced in volume to 400 ml under reduced pressure. The mixture was cooled and the product was collected by filtration. The product was recrystallized from methanol: m.p. 225°-257°, yield: 10 g (34%).

Provenance & Evidence