Diethylamine → HCID 54132934, compound

Participants

Reaction Steps

A solution of 11.7 g of diethylamine in 100 ml of diethylether is added dropwise to a solution of 27.1 g of 1-methylethyl 2,2-dichloro-[(1-chloro)phenylphosphinyl]-acetate in 200 ml of ether at 0°. After stirring at room temperature for 1 hour, the solution is washed with water and with 10% sodium bicarbonate solution, then dried over MgSO4 and stripped to give a dark oil. The reaction product is dissolved in n-butyl chloride, washed with water, contacted with activated carbon, dried over MgSO4 and stripped to give substantially pure 1-methylethyl 2,2-dichloro-[(diethylamino)phenylphosphinyl]acetate.

Provenance & Evidence