HCID 13594143, compound → HCID 23347377, compound

Participants

Reaction Steps

The procedure described in Example XLVII was repeated except that 2-(p-anisyl)-3-(imidazol-1-ylmethyl)indole was the starting material employed in place of 3-(imidazol-1-ylmethyl)-5-methoxyindole, using the same molar proportions as before. In this particular case, the solid product obtained was chromatographed on silica gel and then finally eluted with chloroform/methanol (20:1 by volume). Evaporation of the product-containing eluate then gave a solid material which was crystallized from ethanol to afford pure 2-(p-hydroxyphenyl)-3-(imidazol-1-ylmethyl)indole, m.p. 245°-247° C.

Provenance & Evidence