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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1856083Generated: October 27, 2026

Trifluoroacetic acid → (+/-)-1-[3-(benzoylthio)-2-methyl-1-oxopropyl]-4,5-dihydro-1H-pyrrole-2-carboxylic acid

https://huagongshe.com/reaction/1856083

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantAnisoleHCID 7519—
ReactantHCID 86737144HCID 86737144—
Product(+/-)-1-[3-(benzoylthio)-2-methyl-1-oxopropyl]-4,5-dihydro-1H-pyrrole-2-carboxylic acidHCID 23347609—

Reaction Steps

The t-butyl ester product from part (a) is treated with anisole and trifluoroacetic acid according to the procedure of Example 1(c) to yield (±)-1-[3-(benzoylthio)-2-methyl-1-oxopropyl]-4,5-dihydro-1H-pyrrole-2-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04217458
Source datasetuspto-grants-1980_08
ORD IDord-7cec2a731aa14cbcb1a1166d0516b9f9
Source noteuspto-grants-1980_08