Diisopropylamine → HCID 23346043, compound

HRID 1856142Notes

Reaction equation

HRID 1856142 reaction equation
[N:1]([C:4]1[CH:9]=[C:8]([N:10]=[C:11]=[S:12])[CH:7]=[CH:6][C:5]=1[F:13])=[C:2]=[S:3].[CH:14]([NH:17][CH:18]([CH3:20])[CH3:19])([CH3:16])[CH3:15]>C(#N)C>[F:13][C:5]1[CH:6]=[CH:7][C:8]([NH:10][C:11]([N:17]([CH:18]([CH3:20])[CH3:19])[CH:14]([CH3:16])[CH3:15])=[S:12])=[CH:9][C:4]=1[NH:1][C:2]([N:17]([CH:18]([CH3:20])[CH3:19])[CH:14]([CH3:16])[CH3:15])=[S:3]

Participants

4

Reactant 2

HCID 7912DiisopropylamineHCID 23346040HCID 23346040, compound

Product 1

HCID 23346043HCID 23346043, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

To a solution of 4.2 g. of 2,4-diisothiocyanatofluorobenzene in 100 ml. of acetonitrile is added 4.1 g. of diisopropylamine and the mixture is refluxed for 3 hours. The solvent is removed in vacuo and the residue is crystallized from acetonitrile to yield 5.1 g. of the title compound, melting point 133°-135° C.

Workup

  1. customThe solvent is removed in vacuo
  2. customthe residue is crystallized from acetonitrile
  3. customto yield 5.1 g

Sources & evidence

ORD record
ord-da6c5049f7424d88b2b881f1f716b423
Source dataset
uspto-grants-1980_08
Patent number
US04218396

Reaction notes

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