Diisopropylamine → HCID 23346035, compound

HRID 1856143Notes

Reaction equation

HRID 1856143 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]=[C:9]=[S:10])=[CH:4][C:3]=1[N:11]=[C:12]=[S:13].[CH:14]([NH:17][CH:18]([CH3:20])[CH3:19])([CH3:16])[CH3:15]>C(#N)C>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]([N:17]([CH:18]([CH3:20])[CH3:19])[CH:14]([CH3:16])[CH3:15])=[S:10])=[CH:4][C:3]=1[NH:11][C:12]([N:17]([CH:18]([CH3:20])[CH3:19])[CH:14]([CH3:16])[CH3:15])=[S:13]

Participants

4

Reactant 2

HCID 7912DiisopropylamineHCID 23346039HCID 23346039, compound

Product 1

HCID 23346035HCID 23346035, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

A mixture of 11.1 g. of 4-chloro-1,3-diisothiocyanatobenzene and 10.2 g. of diisopropylamine is refluxed in 250 ml. of acetonitrile for 4 hours. The reaction mixture is cooled and the acetonitrile is removed in vacuo. The residue is crystallized twice from ether to yield 5.0 g. of the title compound, melting point 122°-123° C.

Workup

  1. additionA mixture of 11.1 g
  2. temperatureThe reaction mixture is cooled
  3. customthe acetonitrile is removed in vacuo
  4. customThe residue is crystallized twice from ether
  5. customto yield 5.0 g

Sources & evidence

ORD record
ord-20e2b5e0242348f7a27d5e64702d7ebb
Source dataset
uspto-grants-1980_08
Patent number
US04218396

Reaction notes

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