Taurine → Carbobenzoxy-beta-alanyltaurine

HRID 1856147Notes

Reaction equation

HRID 1856147 reaction equation
[N+](C1C=CC(O[C:11](=[O:25])[CH2:12][CH2:13][NH:14][C:15]([O:17][CH2:18][C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)=[O:16])=CC=1)([O-])=O.[NH2:26][CH2:27][CH2:28][S:29]([OH:32])(=[O:31])=[O:30]>>[C:15]([NH:14][CH2:13][CH2:12][C:11]([NH:26][CH2:27][CH2:28][S:29]([OH:32])(=[O:31])=[O:30])=[O:25])([O:17][CH2:18][C:19]1[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=1)=[O:16]

Participants

3

Reactant 2

HCID 1123TaurineHCID 4095662Z-beta-Ala-ONp

Product 1

HCID 9927496Carbobenzoxy-beta-alanyltaurineYield 82%

Procedure

1.9 g (5.5 mmoles) of N-carbobenzoxy-β-alanine-p-nitrophenyl ester (Biochemistry 4, 1884 1965) are reacted with 0.63 g (5 mmoles) of taurine as described in Example 1 to obtain 1.35 g (82%) of N-carbobenzoxy-β-alanyl-taurine.

Sources & evidence

ORD record
ord-be1229313538440b881240f50aef8d64
Source dataset
uspto-grants-1980_08
Patent number
US04218404

Reaction notes

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