反应详情

66 g (0.3 mole) mesitylenesulphonyl chloride in 37.5 ml pyridine were added dropwise at -5° C. to 11.2 g (0.015 mole) 2-methylaminoethanol. The reaction mixture was kept in a cooler (4° C.) overnight and then poured on ice. 20 ml acetic acid were added and the product was washed with water, taken up in diethyl ether, washed with water and dried with Na2SO4. The solvent was removed in vacuum, giving 55.7 g pale yellow crystals of the title compound, m.p. 94° C.

1. customwas kept in a cooler (4° C.) overnight
2. additionpoured on ice
3. washthe product was washed with water
4. washwashed with water
5. dry with materialdried with Na2SO4
6. customThe solvent was removed in vacuum