Aluminium lithium hydride → HCID 23346565, compound

HRID 1856304Notes

Reaction equation

HRID 1856304 reaction equation
[O:1]1[CH:12]2[C:2]1([CH3:15])[C:3]1([C:9]([CH3:14])([CH3:13])[CH2:10][CH2:11]2)[O:7][CH:6]([CH3:8])[CH:5]=[CH:4]1.[H-].[H-].[H-].[H-].[Li+].[Al+3]>>[CH3:8][CH:6]1[CH:5]=[CH:4][C:3]2([C:9]([CH3:14])([CH3:13])[CH2:10][CH2:11][CH2:12][C:2]2([CH3:15])[OH:1])[O:7]1

Participants

3

Reactant 2

HCID 21226445Aluminium lithium hydrideHCID 23346563HCID 23346563, compound

Product 1

HCID 23346565HCID 23346565, compoundYield 90.5%

Procedure

2.08 g (0.01 M) of 6,7-epoxy-2,6,10,10-tetramethyl-1-oxa-spiro[4.5]dec-3-ene--see method B, letter i--were reduced by means of 570 mg (0.015 M) of LiAlH4 in accordance with the above process. After the usual treatments of washing, drying and evaporation, the fractional distillation of the obtained residue gave 1.9 g (ca. 90%) of 2,6,10,10-tetramethyl-1-oxa-spiro[4.5]dec-3-ene-6-ol, b.p. 80°-90°/0.1 Torr.

Workup

  1. washAfter the usual treatments of washing
  2. customdrying
  3. customevaporation
  4. distillationthe fractional distillation of the obtained residue

Sources & evidence

ORD record
ord-271cad3249754dad85018b8fabe466f0
Source dataset
uspto-grants-1980_08
Patent number
US04218488

Reaction notes

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