Hydrochloric Acid → HCID 23344678, compound

Participants

Reaction Steps

To a solution of ethyl α-azido-α-methyl-4-benzyloxycarbonyl-5,5-dimethyl-2-thiazolidine acetate (3.92 g.) in ethanol (20 ml.) is slowly added 20 ml. of 0.5 N sodium hydroxide solution. The solution is stirred at room temperature overnight, then acidified with 20 ml. of 0.5 N hydrochloric acid. The product is extracted into ethyl acetate and the solution dried over anhydrous sodium sulfate and evaporated leaving α-methyl-α-azido-4-benzyloxycarbonyl-5,5-dimethyl-2-thiazolidineacetic acid.

Provenance & Evidence