Carbonate Ion → N-ethyl-N'-(6-fluoro-3,4'-bipyridin-2'-yl)urea

HRID 185638Notes

Reaction equation

HRID 185638 reaction equation
[Br:1][c:2]1[cH:3][c:4]([NH:8][C:9](=[O:10])[NH:11][CH2:12][CH3:13])[n:5][cH:6][cH:7]1.[C:30](=[O:31])([O-:32])[O-:33].[Cs+:34].[Cs+:35].[F:14][c:15]1[n:16][cH:17][c:18]([B:21]2[O:22][C:23]([CH3:24])([CH3:25])[C:26]([CH3:27])([CH3:28])[O:29]2)[cH:19][cH:20]1>>[c:2]1(-[c:18]2[cH:17][n:16][c:15]([F:14])[cH:20][cH:19]2)[cH:3][c:4]([NH:8][C:9](=[O:10])[NH:11][CH2:12][CH3:13])[n:5][cH:6][cH:7]1

Participants

5

Reactant 4

HCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 121772222-Fluoropyridine-5-boronic acid pinacol esterHCID 592083771-(4-Bromopyridin-2-yl)-3-ethylurea

Product 1

HCID 59208411N-ethyl-N'-(6-fluoro-3,4'-bipyridin-2'-yl)urea

Sources & evidence

ORD record
ord-ff5f39de89aa4718a321ca31cb9c0df8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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