Morpholine → HCID 54228020, compound

HRID 1856495Notes

Reaction equation

HRID 1856495 reaction equation
Br[CH2:2][CH:3]=[C:4]([CH3:9])[CH2:5][N+:6]([O-:8])=[O:7].[NH:10]1[CH2:15][CH2:14][O:13][CH2:12][CH2:11]1>CCOCC>[CH3:9][C:4]([CH2:5][N+:6]([O-:8])=[O:7])=[CH:3][CH2:2][N:10]1[CH2:15][CH2:14][O:13][CH2:12][CH2:11]1

Participants

4

Reactant 2

HCID 8083MorpholineHCID 544497411-Bromo-3-methyl-4-nitro-2-butene

Product 1

HCID 54228020HCID 54228020, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

To a solution of 0.1 Mol of 1-bromo-3-methyl-4-nitro-2-butene in ether at 0° C. was added 0.2 Mol of morpholine and stirred at room temperature for two days. The residue, after filtration and evaporation of the solvent, was purified by column chromatography followed by Kugelrohrdistillation at 140°-150° oven temperature and oil pump vacuum. The product obtained was a yellow oil.

Workup

  1. filtrationThe residue, after filtration and evaporation of the solvent
  2. customwas purified by column chromatography
  3. customfollowed by Kugelrohrdistillation at 140°-150°
  4. customThe product obtained

Sources & evidence

ORD record
ord-843411309e2b40e2b546d991dbccbb7c
Source dataset
uspto-grants-1980_08
Patent number
US04219660

Reaction notes

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