反应详情

To 0.1 Mol of 4-nitro-3-methyl-2-butenol was added 0.1 Mol of melted p-chlorophenylisocyanate. The reaction mixture was allowed to stand at room temperature for several hours, before it was dissolved in hot benzene. After crystallizing overnight a solid by-product was filtered off and the benzene was evaporated. The residue was purified by dissolving in a hot hexane-benzene mixture, decanting, while hot, from an insoluble oil, followed by crystallization in a ice bath. The product was obtained as orange crystals, m.p. 79°-81°.

1. waitto stand at room temperature for several hours, before it
2. customAfter crystallizing overnight a solid by-product
3. filtrationwas filtered off
4. customthe benzene was evaporated
5. customThe residue was purified
6. dissolutionby dissolving in a hot hexane-benzene mixture
7. customdecanting
8. customwhile hot, from an insoluble oil, followed by crystallization in a ice bath
9. customThe product was obtained as orange crystals, m.p. 79°-81°